From Breast Milk to Benchtop: Exploring the Clinical Promise of Human Milk Oligosaccharides

This presentation explores factors such as genetics, health, and diet that influence the composition of human milk oligosaccharides (HMOs) in breast milk. It highlights the critical roles HMOs play in supporting infant digestion, brain development, and immune function. The presentation also examines the clinical significance of HMOs beyond infancy and outlines emerging research directions that may expand their therapeutic applications.

Suggested Performance Indicators: 

7.1.1, 9.1.1, 9.1.4

Learning Objectives:
1. Describe the maternal factors that influence the human milk oligosaccharides (HMO) profile in human milk.
2. Discuss how HMOs influence digestion health, brain development, and immune function.

3. Explore the clinical significance of HMOs, role of HMOs beyond infancy and discover future directions for HMO research.

Speaker:

Lauren Spain, PhD, RDN, LD, CDCES, FANDis a dedicated nutrition professional with extensive experience in leadership, research, and wellness. She currently serves as a Medical Science Liaison in Medical Affairs & Research at Abbott’s Nutrition Division. Her expertise spans pediatric nutrition, wellness programming, and public health initiatives. Dr. Spain earned her PhD in Nutrition and Bachelor of Science in Family and Consumer Sciences at the University of Georgia. She completed her dietetic internship at Emory University Hospital and worked as a Clinical Dietitian prior to obtaining her PhD. Her research focused on protein sources and their effects on pediatric bone health and cognitive function. She previously served as Associated Department Head for Undergraduate Programs at Texas A&M University where she oversaw curriculum and taught both undergraduate and graduate courses. Dr. Spain is active within the nutrition community and has held multiple leadership roles including serving as delegate to the Academy of Nutrition and Dietetics (AND) for the Nutrition Educators for Health Professionals Dietetics Practice Group and President of the Georgia Academy of Nutrition and Dietetics. She recently began her tenure as Director-at-Large for the AND in June 2025. Dr. Spain is an accomplished speaker and clinician, committed to driving innovative care in nutrition, health, and wellness. 

Updated November 2025